The Molecular Basis of Inheritance
AP Biology Instructor: Mr. Buckley

1/2. In a large paragraph or two, explain Griffith's experiment which proved the process of bacterial transformation.

3. What did Avery, McCarty, and McLeod discover?

4. What did Hershey and Chase discover?

5. Chargaff's Law involves a particular regularity involving the nitrogenous bases in DNA. Explain this.

6. What did Watson and Crick discover?

7. What is a double helix?

8. How did the Watson and Crick model of DNA explain Chargaff's rules?

9/10. Explain the difference between the conservative, semi-conservative, and dispersive models of DNA replication.

11. Which model of DNA replication was supported by Watson and Crick's work?

12. The molecule DNA is made up of nucleotide subunits. What three parts must make up a nucleotide subunit?

13. What are origins of replication?

14. What is a replication fork?

15. What do DNA polymerases do in the replication process?

16. Explain what is meant when it is stated that the two strands of DNA are antiparallel.

17. What is the role of DNA helicase in the replication process?

18. DNA replication has remarkable few errors. Briefly justify this statement.

19. Explain the process of excision repair of DNA.