1.  Flower color in primrose plants is controlled by an individual  gene.
     The  sudden  appearance of one white flowering primrose in a plant breeder’s
     field of  red primrose plants is most likely due to
     (1.)   a change in the amount of glucose produced during photosynthesis
     (2.)   the use of a new natural fertilizer on the field
     (3.)   rapid mitotic divisions within the developing  seeds
     (4.)   a random change in the structure of  DNA during meiosis

2.   The gene-chromosome theory states that  (1.) chromosomes from both parents always
      have identical genes  (2.) homologous chromosomes do not have alleles
      (3.) genes exist at definite loci in a linear sequence on chromosomes
      (4.) Mendel's principles no longer apply to genetics

3.  Which statement best describes the process of crossing over?  (1.) It takes place
      between homologous chromosomes and results in new gene combinations.  (2.) It
      takes place between homologous chromosomes and results in an increased gene
      mutation rate.  (3.)  It takes place between nonhomologous chromosomes and results
      in an increased gene mutation rate.  (4.) It takes place between nonhomologous
      chromosomes and results in new gene combinations.

4  White short-horned cattle and Black Angus cattle have been crossed to produce
    offspring with superior  beef  and  rapid  growth  qualities.  This process  of
    choosing  organisms  with  the  most desirable traits for mating is known as
    (1.)  cloning  (2.) selective breeding  (3.) biodiversity  (4.) genetic engineering
 
5.   A structure found in the nucleus of a cell is shown in the diagram at the right. The information contained in the diagram best illustrates the (1.) law of segregation  (2.) concept of nondisjunction  (3.) theory of natural selection  (4.) gene-chromosome theory

Use the information provided in the chart below and your knowledge of the living environment to answer questions 6 and 7 which follow.
 
6.  The arrangement of chromosomes in the diagram at the right is known as a  (1.) karyotype  (2.) centromere  (3.) mutation rate  (4.) genotype

7.  If the chromosomes of a female were arranged in chart form like the chromosomes of this male, the chart would  (1.) be identical to that of the male  (2.) appear different in one chromosome pair  (3.) contain more chromosomes  (4.) have one-half the number of chromosomes

8.  Mutations can be transmitted to the next generation only if they are present in (1.) brain cells
     (2.) body cells  (3.) sex cells  (4.) muscle cells

9.  Sometimes a section of a chromosome is lost during meiosis. This loss results in a change
     in genetic material known as   (1.) deletion  (2.) replication  (3.) crossing over  (4.) polyploidy

10. In which situation could a mutation be passed on to the offspring of an organism?
      (1.) Ultraviolet radiation causes skin cells to undergo uncontrolled mitotic division.
      (2.) A primary sex cell in a human forms a gamete that contains 24 chromosomes.
      (3.) The DNA of a human lung cell undergoes random breakage.
      (4.) A cell in the uterine wall of a human female undergoes a chromosomal alteration.

11.  Bacteria that produce colonies containing a red pigment were distributed on nutrient agar
       and exposed to ultraviolet light for several days. The colonies that developed were red,
       with the exception of one colony that was white. The appearance of this white bacterial
       colony most likely resulted from  (1.) codominance  (2.) a mutation  (3.) synapsis
       (4.) multiple alleles

12.  Which genetic change is best described by the following statement. A random change in
        the base sequence of DNA results in an alteration of a polypeptide.
        (1.) Translocation (2.) Deletion  (3.) Addition  (4.) Gene Mutation

13.  Which genetic change is best described by the following statement. A
       chromosomal rearrangement is formed after a section breaks off from one chromosome
       and becomes attached to a nonhomologous chromosome. (1.) Translocation
       (2.) Deletion  (3.) Addition  (4.) Gene Mutation

14.  Substances that increase the chance of gene alterations are known as (1.) mutagenic agents
       (2.) chromosomal agents  (3.) genetic agents  (4.) adaptive agents

15.  A gene mutation may be transmitted to offspring if the mutation occurs within
       (1.) an egg cell   (2.) cells of the uterus   (3.) muscle cells   (4.) blood cells

16.  The mutation rates in Drosophila will most likely increase after exposure to
       (1.) ultraviolet radiation  (2.) oxygen gas   (3.) yeast growing on a nutrient medium
       (4.) extremely cold temperatures

17.  Which change in chromosome structure involves the transfer of one section of a
       chromosome to a nonhomologous chromosome?  (1.) nitrogenous base substitution
       (2.) crossing-over of linked genes  (3.) translocation  (4.) gene mutation

18.  Which statement best describes a chromosomal alteration?  (1.) It never affects the
       phenotype of an organism.  (2.) It always produces a recessive genotype in an organism.
       (3.) It may affect the phenotype of an organism.  (4.) It never has an effect on the genotype
       of an organism.
 
19.  The diagram at the right shows some chromosomal alterations. Which chromosome represents an alteration known as a deletion?
(1.) 1  (2.) 2  (3.) 3  (4.) 4

20.  A mutation may be passed on to future generations if it occurs within specialized cells of the
       (1.) stomach  (2.) pancreas  (3.) liver  (4.) ovary

21.  An example of a mutagenic agent is  (1.) an amino acid  (2.) acetylcholine
       (3.) ultraviolet radiation  (4.) maltase

22.  A single change in the sequence of nitrogenous bases in a DNA molecule would most
       likely result in  (1.) crossing-over  (2.) nondisjunction of chromosomes
       (3.) polyploidy  (4.) a gene mutation

23.  Some weed killers, insecticides, and food additives alter the DNA of certain cells. Because
       of this effect, these substances are known as  (1.) auxins  (2.) meristems  (3.) mutagens
       (4.) autosomes

24.  In a species of plant, the sudden appearance of one plant with a different leaf structure
       would most likely be the result of  (1.) stable gene frequencies
       (2.) slow environmental changes  (3.) chromosomal mutations (4.) asexual reproduction

25.  Identical twins were born with genes for a genetic disorder that can be controlled by
       diet.   Both twins were placed on this diet, which excludes a certain amino acid.
       However, one twin chose not to follow the diet and developed the genetic disorder. The
       other twin followed the diet and did not develop the disorder. This difference between
       the twins illustrates that (1.) gene expression is not influenced by biochemical factors
       (2.) gene expression is influenced by the environment  (3.) identical twins do not always
       have the same genotype  (4.) the genetic disorder is inherited by identical twins, only
 
26.  The diagram at the right illustrates what happens to the fur coloration of a Himalayan hare after exposure to a low temperature. This change in fur coloration is most likely due to  (1.) the effect of heredity on gene expression
(2.) environmental influences on gene action 
(3.) the arrangement of genes on homologous chromosomes  (4.) mutations resulting from a change in the environment 

27.  A garden hose that had been lying on a green lawn for several days was removed.
       Which statement best explains the presence of yellow grass in the area where the hose
       had been?  (1.) The lack of sunlight under the hose altered the genotype of the grass.
       (2.) The hose altered genes in the grass, causing the grass to switch from autotrophic
       to heterotrophic nutrition.  (3.) Gene expression is not affected by the environment.
       (4.) The lack of sunlight under the hose affected chlorophyll production.

28.  Artificial selection is illustrated by  (1.) random mating taking place in a population
       (2.) a gardener producing a new hybrid by cross-pollinating plants
       (3.) the appearance of a new species on an isolated island
       (4.) wind assisting the pollination of grass in a field

29.  Breeders have developed a variety of chicken that has no feathers. Which methods were
       most likely used to produce this variety?  (1.) artificial selection and inbreeding
       (2.) regeneration and incubation  (3.) grafting and hybridization
       (4.) vegetative propagation and binary fission

30.  When the bacterium Serratia marcescens is grown on a sterile culture medium in a petri dish
       at 30°C, the bacterial colonies will be cream colored. When this same bacterium is
       cultured under identical conditions, except at a temperature of 25°C, the colonies will be
       brick red. This difference in color is most likely due to the  (1.) type of nutrients in the
       culture medium  (2.) effect of temperature on the expression of the gene for color
       (3.) sterilization of the culture medium  (4.) effect of colony size on the synthesis of
       color pigments

31.  A cattle breeder wished to develop a strain of cattle that would produce large quantities
       of meat per animal. He chose a bull and a cow that most nearly met his goals for breed
       size. From their calves, he again chose the male and female offspring that most nearly met
       his goals. After several generations of this style of breeding, the breeder developed a herd
      of high-yield cattle. In order to maintain this herd of high-yield cattle, which technique
      should the cattle breeder use?  (1.) vegetative propagation  (2.) genetic recombination
      (3.) hybridization  (4.) inbreeding

32. In fruit flies with the curly wing mutation, the wings will be straight if the flies are kept at
      16°C, but curly if they are kept at 25°C. The most probable explanation for this is that
      (1.) fruit flies with curly wings cannot survive at high temperatures  (2.) high
      temperatures increase the rate of mutations  (3.) the environment influences wing phenotype
      in these fruit flies  (4.) wing length in these fruit flies is directly proportional to temperature

33.   Scientists conducted a study of identical twins who were separated at birth and raised
        in different homes. They found that in some sets of twins the individuals showed a
        marked difference in intelligence. The most likely explanation for this difference is that
        (1.) expression of inherited traits can modify the environment
        (2.) environment can influence the development and expression of inherited traits
        (3.) intelligence is a sex-linked trait
        (4.) nondisjunction occurred in the autosomes of one twin but not the other twin

Use the diagram below and your knowledge of the living environment to answer questions 34 through 36 which follow.
34.  Which situation would form a normal human male?

35.  Which situation would form a normal human female?

36.  Which situation would produce a female zygote having a nondisjunction of the 23rd chromosome pair?

37.  Which diagram represents a sperm that can unite with a normal egg to produce a zygote that will develop into a normal human male embryo?
(1.) 1  (2.) 2  (3.) 3  (4.) 4

38.  In humans, the gene for red hair and the gene for freckles are often inherited together
       because both genes are located on the same chromosome. This observation best illustrates
       the concept of  (1.) gene linkage  (2.) dominance  (3.) independent assortment
       (4.) hybridization

Note that question 39 has only three choices.

39.  Which statement best describes the relationship between the number of genes and number
        of chromosomes in human skin cells?  (1.) There are more genes than chromosomes in
        skin cells.  (2.) There are more chromosomes than genes in skin cells.  (3.) There are an
        equal number of chromosomes and genes in skin cells.

40.  A woman has a gene that causes a visual disorder.  To prevent the gene from appearing in
       future generations, the defective gene would have to be repaired in the mother's
       (1.) eye  (2.) uterus  (3.) nervous system  (4.) reproductive cells

Now hopefully some correct answers! Send any information about errors or comments to jbuckley@ekcs.neric.org

Multiple Choice Section

1.    4
2.    3
3.    1
4.    2
5.    4
6.    1
7.    2
8.    3
9.    1
10.    2
11.    2
12.    4
13.    1
14.    1
15.    1
16.    1
17.    3
18.    3
19.    4
20.    4
21.    3
22.    4
23.    3
24.    3
25.    2
26.    2
27.    4
28.    2
29.    1
30.    2
31.    4
32.    3
33.    2
34.    4
35.    1
36.    2
37.    2
38.    1
39.    1
40.    4
 

Free Response Section

1.   List and describe at least three specific changes in chromosome structure we discussed.

2.  List and describe at least three techniques used to select for better plants and animals.


Free-Response Answers

1.  Some changes in chromosome structure include:

 Translocation: transfer of one section of a chromosome to a nonhomologous chromosome

Addition: a portion of one chromosome is attached to another chromosome

Deletion: a portion of a chromosome is taken away from a chromosome

Inversion: a portion of a chromosome breaks off and then becomes reattached to the same chromosome in an inverted (upside down) fashion



2.   Artificial Selection-- individuals with desirable traits are mated to produce offspring with
      those traits

      Inbreeding-- offspring produced by artificial selection are mated with one another to
      reinforce those desirable traits

     Hybridization-- crossing two individuals with different desirable traits to produce offspring with
    a combination of both desirable traits   ex.

English shorthorn cattle X Brahman cattle ->Santa Gertrudis cattle (good beef)(heat resistance)
      (good beef)                 (heat resistant)

d. Mutations may be preserved by vegetative propagation. (ex. seedless oranges)

e.  Recombinant DNA (genetic engineering) --- new varieties of plants and animals can be
     created by manipulating the genetic instructions of these organisms to produce
     new characteristics